Dec 11, 2018

Webinar: Interfacing Musculoskeletal and Finite Element Models to Study Bone Structure and Adaptation

Learn about interfacing musculoskeletal models with FE models, methodological solutions and an OpenSim plugin to extract muscle force directions

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Details

Title: Interfacing Musculoskeletal and Finite Element Models to Study Bone Structure and Adaptation
Speakers: Luca Modenese and Andrew Phillips, Imperial College London
Time: Tuesday, December 11, 2018 at 10:00 a.m. Pacific Standard Time

Abstract

Musculoskeletal models can be used to simulate human motion and study the muscle and joint reaction forces occurring during various activities. The predicted internal forces can in turn be applied as external loads in finite element (FE) models of biological structures, e.g. bone and cartilage, to calculate internal stresses and strains and investigate their behaviour and adaptation in a biofidelic mechanical environment. In this webinar, we will present our experience in interfacing musculoskeletal models with FE models, describing methodological solutions we developed to apply force sets from musculoskeletal models to deformable models of bones, including consideration of load application, boundary conditions and an OpenSim plugin to extract muscle force directions. We will also present as example some computational studies where we applied these methodologies to bone structure optimization in the femur and pelvis bones and to the investigation of prenatal biomechanics.

Below are some links to learn more about topics mentioned during the webinar:

• Plugin to extract the muscle lines of action: https://simtk.org/projects/force_direction
• Codified procedure and scripts to generate musculoskeletal models from MRI images: https://simtk.org/projects/subj-spec-model
• Open-access research papers with description of the bone adaptation methodology mentioned during the webinar applied to the femur and to the pelvis
• Open-access research papers describing bone fracture modelling and a metamodel for bone adaptation
• Further information can be found at www.imperial.ac.uk/structural-biomechanics