Jan 24, 2017

Webinar: Musculoskeletal simulations combining multiscale data and finite element modeling of the knee

Learn about linking joint-level deformable finite element models with multibody musculoskeletal simulations

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A recording of the event is available for viewing. Visit https://simtk.org/projects/knee_model to find models mentioned in the webinar and to continue the discussion from the webinar Q&A session. To learn more about the work, check out the publications listed at the bottom of this page.

Details

Title:Musculoskeletal simulations combining multiscale data and finite element modeling of the knee
Speakers: Kevin Shelburne, Alessandro Navacchia, and Azhar Ali, University of Denver
Time: Tuesday, January 24, 2017 at 10:00 a.m. Pacific Standard Time

Abstract

Musculoskeletal simulations of movement are traditionally performed using rigid multibody models with simplified joint representations that do not account for the deformability and complex motion of biological tissues and articulations. However, several pathological conditions and treatments, such as osteoarthritis and total joint replacement, can be best investigated within a deformable modeling framework. Local tissue deformation is usually modeled with the finite element method that discretizes an arbitrary geometry into a mesh of deformable elements. While finite element models have been widely used to describe the tissue behavior at the organ/joint level (e.g. bone, knee joint), the interaction between this local level and the neuromuscular behavior at the whole-body scale is often neglected. We will present a conceptual overview of multi-scale musculoskeletal modeling, and two examples of multi-scale approaches in a sequential fashion that link the outputs from a multibody OpenSim musculoskeletal simulation to joint-level deformable finite element models.

Webinar highlights:

  • Conceptual overview of multi-scale musculoskeletal modeling.
  • Presentation of two examples of the multi-scale sequential modeling approach that links multibody simulations to deformable finite element models.


 Workflow of the multi-scale sequential modeling approach used to estimate deformable contact mechanics for total knee replacement patients performing activities of daily living.
Figure 1. Workflow of the multi-scale sequential modeling approach used to estimate deformable contact mechanics for total knee replacement patients performing activities of daily living.


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